Brendan Rodgers opts with Luis Suarez up front, leaving strikers Daniel Sturridge and Fabio Borini on the bench for trip to Man Utd, while Joe Allen is given a place in midfield.
Wayne Rooney misses out as expected after failing to return in time from the the injury he picked up on Christmas Day.
Manchester United: De Gea, Rafael, Ferdinand, Vidic, Evra, Cleverley, Carrick, Kagawa, Young, Welbeck, Van Persie
Liverpool: Reina, Wisdom, Johnson, Agger, Skrtel, Lucas, Gerrard, Allen, Downing, Sterling, Suarez
Match fact: Liverpool have not kept a clean sheet on their last 9 visits to Old Trafford in PL & Cup and they have lost 8 of those games
TAKE FIVE: Man Utd v Liverpool is the fantasy5live.com match this weekend