Wayne Rooney scored a hat-trick as an inspired Manchester United side piled on the misery for under fire Arsenal manager Arsene Wenger.
The current league champions thumped an astonishing eight goals past their rivals, condemning them to their biggest ever Premier League defeat.
United made a flying start, but the game remained goalless until the midway point of the first half, when Anderson chipped a ball over the Gunners defence and Danny Welbeck headed home from close range.
Almost immediately, Arsenal had the chance to equalise when Jonny Evans pulled Theo Walcott back in the area. However, David de Gea was equal to Robin Van Persie’s effort, diving to his right to push the spot-kick round the post.
United straight away made Arsenal pay as Ashley Young curled home a superb effort from 25 yards to make it 2-0.
Shortly before half-time Wayne Rooney added a third, his 150th Red Devils goal, by curling in a free-kick from the edge of the area after Carl Jenkinson had fouled Young.
A stoppage-time strike from Theo Walcott gave Arsenal a glimmer of hope, but it proved to be fleeting as United continued their dominance after the break; Rooney, Nani and Park the scorers in a six-minute blitz which put the hosts 6-1 up.
Van Persie scored a consolation goal to make it 6-2 on 74 minutes, but defender Carl Jenkinson was sent off for a second yellow card two minutes later, leaving Arsenal vulnerable to more United onslaught.
Eight minutes from time Rooney completed his deserved hat-trick from the penalty spot, netting after Patrice Evra had been fouled by Walcott, while Young piled yet more misery on Wenger’s team in stoppage time with another sublime long-range curler.
The final whistle could not come soon enough for the visitors. Afterwards, Rooney hailed a fantastic team performance, “The performance today was incredible and we deserved the result. Whether or not Arsenal have a full-strength squad every time we play them we have a go and try score. They had some players out but that should take nothing away from us.”
United now lie top of the table, as Arsenal languish above the unchartered territories of the relegation zone.